Former T500 ana main, I played with this build a lot. Currently All-stars with a 36-6 record W/L.
It's the Ultimate Heatlh and Sleep combo. Nobody can touch you. You'll finished with 600 health, movement ability and a very powerfull sleep that you can't miss (500% projectile size) Easily the best build i've played for ana.
1Round 1
Round 1
Power: Sleep Regimen. THIS IS A VERY IMPORTANT FIRST POWER. You want this power first since it gives you 50 health + 10 health each time you sleep an enemy (It stays round after round so you want to equip this as soon as possible)
Items:
- Armored Vest, you'll be a mini-tank on ana on the first round. 350 hp.
- Weapon Speed and Attack to farm more coins
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2Round 2
Round 2: You wanna get Tranquilizer no matter what. Sell everything if possible to get it. You'll be able to land a LOT more sleep. And more sleep means more health.
If you have 14k after round 1 (Wich is very possible) Then pick Dash boots. It'll make you very mobile, combine this with your health, you'll be unkillable.
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3Round 3
Round 3: Power: Comfy Cloud. With how easy sleep are to hit, Comfy clouds is the perfect combo. Shug your sleep in the enemy and you'll most likely sleep 1-2 person(s). Throw a nade and you win the teamfight. Super good.
Items: Go for Lethal Dose, more damage, more lifesteal. This is the best build for your sleep. You'll be able to solo kill a genji or a reaper on your backline.
If you have the cash, always a good idea to go with dash boots or potent projectiles. It'll make you life easier overall in all scenario.
If you still have overflow, go for weapon power.
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4Round 4
At this stage, you should have Dash Boots and Potent Projectile at least.
Then you can start to spend the remaining of your build on Weapon Damage. Best option for ana is Eye of the Spider since she can't crit.
An item I also found enjoying a lot was Amari's Antidote. It can really be a game changer in some fight.
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5Round 5
Round 5: Power: Since the sleep is maxed, go for Our Turn. Can't go wrong with a 3-4 man Nano in a team fight.
Items, You should buy Eye of the Spider for sure at round 5. Then have fun with some weaper power if you have the money for it.
As always., Eye of the Spider can be replace with Amari's Antidote.
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6Round 6
This should be your final build. You can sell Potent Projectiles if you ever want more weapon power or something else you might like.
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7Round 7
As last Power, I usually go for a Nano Boost buff. You'll farm a lot of Nano in the game.
