It's important to assess that this build is not viable unless you have a pumper main-healer who can multi-heal (Mercy, Lucio, Kiriko) and is exclusively focused on healing. If you have a Zen or Ana on your team, playing this build WILL decrease your chances of winning.
Hold Primary Fire to spew purple orbs nonstop, and to grant a cycling +20% damage buff ([Deconstruction]). If possible, keep your tank as the fulcrum by which they receive your heals while spewing purple orbs at enemies. Time your Orb ability usage to spew near the same time as your Primary-Fire generated orbs for additional burst. When you ult, time all this just before your ult. The ult alone can do a maximum of 431 DPS in its cone to every unit hit, not taking into account your full-powered orbs
Remember that Attack Speed amplifies both your orb-spew speed, as well as a MULTIPLICATIVE effect on your ultimate (AP increases damage, while AS makes that damage apply faster. It's probably not intended that AS affects your ult, which is why it's so powerful).
The high-level math behind this build, is that everything stacks MULTIPLICATIVELY. Basically: [Base orb damage] x [AP multiplier] x [AS multiplier] x [[Deconstruction] 20% multiplier] x [[Destruction’s Divide] 30% multiplier]. That's why, for raw damage, getting those powers makes the expontential curve happen earlier. It's also why raw AP and AS is better than anything else; though, Cybervenom seems to be condusive to winning despite being a bit stat inefficient.
If you want to flex in more heals, getting [Phantasm] round 3 can make you do more burst heals or damage (3 full powered orbs instead of 2), but does delay your maximum ult damage with [Destruction’s Divide]
Stat-wise [Three-tap Tommygun] works really well here, but for the most part it isn't practical to use Secondary Fire when you could just be nonstop Primary Firing, spewing orbs, and healing your tank a bit more
At higher MMR/ELO, you're vulnerable during your ultimate. Getting 25% lifesteal and [Phantasmic Flux] can remove this issue, while also keeping you constantly due to all the damage you're dealing. If you need additional tank, [Lumerico Fusion Drive] and [Nebula Conduit] are your main go-tos.
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