Strong Against

Mercy
Support

Junker Queen
Tank

Ana
Support
Weak Against

Reinhardt
Tank

Zarya
Tank

D.Va
Tank
Full guide on how to solo queue Juno to All-Star. Guide originally published by u/zero41120: https://www.reddit.com/r/JunoMains/comments/1kguwst/i_solo_juno_to_allstar_and_here_is_my_build_guide/
Full credit to u/zero41120, however I have made some adjustments based on my own experience playing this build.
The following are the recommended powers, see each round for why they are chosen. - [Medimaster] : Allows [Mediblaster] to critically hit allies and enemies. Juno's crit multiplier is 1.25x (not 1.5x or 2x), meaning a healing burst becomes 72 x 1.5 = 108, and a damage burst is 90 x 1.5 = 135 - [Stinger] : [Mediblaster] deals an additional 10 damage to enemies over 1 second (does not stack). Note that there is audio glitch in the game that the damage overtime sound doesn't stop even if the target dies somehow. So be ready for that. - [Medicinal Missiles] : [Pulsar Torpedoes] heal for an extra 30 life and cause allies hit to receive 50% more healing for 3 seconds. - [Pulsar Plus] : [Pulsar Torpedoes] gain 1 additional charge. - [Blink Boosts] : [Glide Boost] gains 2 additional charges and has a 65% reduced cooldown, but its duration is reduced by 75%. - [Black Hole] : [Hyper Ring] slows the Move Speed of enemies who pass through it by 35% for 1 second. - [Hyper Healer] : Allies affected by [Hyper Ring] gain 50 Overhealth.
Powers to Generally Avoid (and Why): - [Cosmic Coolant]: Cooldown reduction based on targets hit is inconsistent. Bad for muscle memory - [Torpedo Glide]: Damage-based cooldown reduction isn't dependable. Bad for muscle memory - [Rally Ring]: Relies on unpredictable teammate behavior. Note that same teammate can only trigger this once. - [Orbital Alignment]: Juno's ultimate charges too slowly for consistent use. - [Stellar Focus]: Similar to Orbital Alignment; good positioning offers most of the benefit without using a power slot.
General Item Buying Rule of Thumb: Unless the item grants some special attribute, buying four common items (≈4000) is often better than 1 rare item ≈4000. Buying 2-3 rare items (≈8000-12000) is often better than 1 epic item (≈10000-13500)
Specific Matchups
vs AP Burst Enemy - [Reinforced Titanium] : Reduces AP damage by 15%. - [Divine Intervention] : Reduces all damage by 15% and triggers self shield regeneration. Especially strong for Juno and Zarya who have nature shields to take immediate advantage of the regen effect.
vs Diver Enemy - [Crusader Hydraulics]: Reduces weapon damage by 10%. - [Nebula Conduit]: Converts 15% incoming damage into damage over time for 3 seconds. Useful against burst dives, gives time for allies to react and disrupts combos.
vs Headshot Enemy - [Iron Eyes]: Reduces headshot damage. Follow-up with one of: - [Crusader Hydraulics]: 10% weapon damage reduction - [Divine Intervention]: 15% all damage reduction and shield regen
Rounds
Player Loadout
Powers
Items
Optional Items
Stats Impact
Core
Stats
Round Notes
1st Power: Aim for something that helps earn cash quickly.
- [Medimaster] Pick if: Enemy tank is Zarya or Orisa (easy headshots from the front); your team has Zarya or Junker Queen (easy healing headshots from behind). Only take if your aim is good.
Avoid if: Your team has Reinhardt, Orisa, or D.Va (unreliable healing headshots from behind).
-
[Medicinal Missiles] Pick if: The other support is Mercy or Ana (you can outpace their single-target healing for more cash).
-
[Pulsar Plus] Pick if: The map preview shows good torpedo maps like Throne of Anubis, Colosseo, or Redwood Dam (especially Redwood), where you can use Torpedo effectively
-
[Blink Boosts] Pick if: Enemy tank is Rein, D.Va, or Orisa; enemy DPS includes Genji or Cassidy (helps escape high-threat situations, like Orisa's ult).
Must Pick:
- [Armored Vest]: Consistent and valuable.
Pick 2 of the Following 3 Options:
- [Compensator]: A full burst is 90 damage (12 bullets x 7.5), healing is 72 (12 x 6). This adds ~4.5 extra damage or ~3.6 extra healing per burst.
- [Weapon Grease]: Increases rate of fire from 1.29 bursts/sec to ~1.35 bursts/sec. Reload speed (1.8s) remains unchanged.
- [Power Playbook]: Pick only if the map favors torpedoes or you took Medicinal Missiles as your first power.
Correction: Medimaster grants a 1.25x headshot multiplier, not 1.5x